PLGA micro/nanoparticle vaccination elicits non-tumor antigen specific resident memory CD8<sup>+</sup> T cell protection from hepatocellular carcinoma-Reference-Cited by-同舟云学术

PLGA micro/nanoparticle vaccination elicits non-tumor antigen specific resident memory CD8⁺ T cell protection from hepatocellular carcinoma

Published:2024 Issue:25 Volume:16 Page:12149-12162
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Li Pan¹²^ORCID,Zhai Zihe³,Fang Jiawen¹,Wang Ruo²,Li Weiqi¹,Wang Beiduo³,Wang Jinglei¹,Zhu Jiaqi²,Bing Feng²,Pan Qiaoling²,Gao ChangYou³^ORCID,Lu ShaoHong¹

Affiliation:

1. Engineering Research Center of Novel Vaccine of Zhejiang Province, Hangzhou Medical College, Hangzhou, 310051, China

2. State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, 79 Qingchun Rd., Hangzhou City, 310003, China

3. MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China

Abstract

Non-tumor antigen specific CD8+ memory T cells (TRMs) can be activated by vaccination and work synergistically with tumor-specific T cells for anti-tumor immunity.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NR/D4NR00554F

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