Poly(trimethylene carbonate) flexible intestinal anastomosis scaffolds to reduce the probability of intestinal fistula and obstruction

Abstract

The tissue engineering scaffold of electrospun poly(trimethylene carbonate) (PTMC) has excellent biomimetic extracellular matrix properties, biocompatibility and biodegradability. This study reports the preparation of electrospun PTMC fibers loaded with triclosan (TCS) into an intestinal anastomosis scaffold, which can respond well to the complex biological environment during intestinal anastomosis repair and is beneficial to tissue healing.