Self-assembly of alkylated lysine-dendron oxytocin amphiphiles for enhanced stability and sustained pharmacological activity-Reference-Cited by-同舟云学术

Self-assembly of alkylated lysine-dendron oxytocin amphiphiles for enhanced stability and sustained pharmacological activity

Published:2023 Issue:93 Volume:59 Page:13855-13858
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Xie Fengjuan¹,Lin Yingying¹,Andersson Åsa²,Vetter Irina²³,Zhao Liang¹,Wan JingJing¹^ORCID

Affiliation:

1. School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, P. R. China

2. Institute of Molecular Bioscience, The University of Queensland, St Lucia, QLD 4072, Australia

3. School of Pharmacy, The University of Queensland, Woolloongabba, QLD 4102, Australia

Abstract

Herein, we designed alkylated lysine-dendron oxytocin amphiphiles (ALOAs) 1G-OTK and 2G-OTK, which were self-assembled into spherical nanoparticles and nanostrips, respectively, and showed superior stability compared to native oxytocin.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC03801G

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1. Oxytocin enables maternal behaviour by balancing cortical inhibition

2. Effects of long-term treatment with oxytocin in chronic constipation; a double blind, placebo-controlled pilot trial

3. Bioresponsive nanogels for protein delivery

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