Targeted inhibition of pyroptosis <i>via</i> a carbonized nanoinhibitor for alleviating drug-induced acute kidney injury-Reference-Cited by-同舟云学术

Targeted inhibition of pyroptosis via a carbonized nanoinhibitor for alleviating drug-induced acute kidney injury

Published:2024 Issue:23 Volume:12 Page:5609-5618
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Ji Yanjun¹²,Wang Huan¹^ORCID,Liu Xinchen³,Zhu Zitong¹²,Song Anjun¹²,Chen Li¹²,Ren Jinsong¹²^ORCID

Affiliation:

1. State Key Laboratory of Rare Earth Resources Utilization and Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China

2. School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China

3. Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun 130021, P. R. China

Abstract

A carbonized nanoinhibitor derived from a small molecule pyroptosis inhibitor is constructed to ameliorate drug-induced acute kidney injury by inhibiting pyroptosis with a favorable kidney-targeting ability and high therapeutic efficacy.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/TB/D4TB00382A

Reference28 articles.

1. Gasdermins and pyroptosis in the kidney

2. Pyroptosis in inflammatory diseases and cancer

3. Prussian Blue Nanozyme as a Pyroptosis Inhibitor Alleviates Neurodegeneration

4. Mitochondrial‐Targeted Delivery of Polyphenol‐Mediated Antioxidases Complexes against Pyroptosis and Inflammatory Diseases

5. Cell pyroptosis in health and inflammatory diseases

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