Detection of the SARS-CoV-2 spike protein in saliva with Shrinky-Dink© electrodes

Author:

Zakashansky Julia A.1234ORCID,Imamura Amanda H.5678ORCID,Salgado Darwin F.9234,Romero Mercieca Heather C.9234ORCID,Aguas Raphael F. L.9234,Lao Angelou M.9234,Pariser Joseph9234,Arroyo-Currás Netzahualcóyotl101112413ORCID,Khine Michelle9234ORCID

Affiliation:

1. Materials Science and Engineering

2. University of California – Irvine

3. Irvine

4. USA

5. Instituto de Química de São Carlos

6. Universidade de São Paulo

7. São Paulo

8. 13566-590 Brazil

9. Biomedical Engineering

10. Department of Pharmacology and Molecular Sciences

11. Johns Hopkins School of Medicine

12. Baltimore

13. Department of Chemical and Biomolecular Engineering

Abstract

We introduce a simple, scalable, and portable electrochemical aptamer-based system for detection of the SARS-CoV-2 spike protein in saliva with attomolar sensitivity.

Funder

National Institutes of Health

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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