tBuOK/DMSO/O2catalyzed direct α-C(sp3)–H alkylation with styrenes: productive α-amino radicals for hydroaminoalkylation-Reference-Cited by-同舟云学术

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^tBuOK/DMSO/O₂catalyzed direct α-C(sp³)–H alkylation with styrenes: productive α-amino radicals for hydroaminoalkylation

Published:2023 Issue:11 Volume:10 Page:2714-2720
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Yan Zhangqiang¹,Zhang Zhen¹,Wen Tao¹,Ye Lihua¹,Jin Bo¹,Zhang Chihong¹,Wang Wenkun¹,Chen Zhong-Ning¹²^ORCID,Cai Hu¹^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering, Nanchang University, Nanchang 330031, Jiangxi Province, People's Republic of China

2. Fujian Institute of Research on the Structure, Chinese Academy of Science, Fuzhou, Fujian 350002, People's Republic of China

Abstract

Direct α-C(sp3)–H alkylation of hydroaminoalkylation (HAA) catalyzed bytBuOK/DMSO/O2from α-aryl benzylamines with styrenes is reported.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D2QO01911F

Reference47 articles.

1. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

2. U.S. FDA Approved Drugs from 2015–June 2020: A Perspective

3. New Strategies for the Transition-Metal Catalyzed Synthesis of Aliphatic Amines

4. Hydroaminoalkylation for the Catalytic Addition of Amines to Alkenes or Alkynes: Diverse Mechanisms Enable Diverse Substrate Scope

5. CatalyticC-Alkylation of Secondary Amines with Alkenes

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