Synthesis, preclinical evaluation and molecular modelling of macrocyclic appended 1-(2-methoxyphenyl)piperazine for 5-HT1A neuroreceptor imaging-Reference-Cited by-同舟云学术

Synthesis, preclinical evaluation and molecular modelling of macrocyclic appended 1-(2-methoxyphenyl)piperazine for 5-HT1A neuroreceptor imaging

Published:2016 Issue:9 Volume:6 Page:7288-7301
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Hazari Puja Panwar¹²³⁴,Prakash Surbhi¹²³⁴⁵,Meena Virendra Kumar¹²³⁴⁵,Singh Niraj¹²³⁴,Chuttani Krishna¹²³⁴,Chadha Nidhi¹²³⁴,Singh Pooja¹²³⁴⁵,Kukreti Shrikant⁵⁶⁷⁴,Mishra Anil Kumar¹²³⁴

Affiliation:

1. Division of Cyclotron and Radiopharmaceutical Sciences

2. Institute of Nuclear Medicine and Allied Sciences

3. Delhi-110054

4. India

5. Department of Chemistry

6. University of Delhi

7. Delhi-110007

Abstract

An efficient approach in the design and synthesis of a multi-functional chelating agent based on 1-(2-methoxyphenyl)piperazine for targeting 5-HT_1A receptors in brain was envisaged.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA13432C

Reference40 articles.

1. Visualisation of serotonin-1A (5-HT1A) receptors in the central nervous system

2. [18F]MPPF as a tool for the in vivo imaging of 5-HT1A receptors in animal and human brain

3. Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult

4. Serotonin type-1A receptor imaging in depression

5. 5-HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors;Journal of Medicinal Chemistry;2022-08-08

2. 5-HT1A targeting PARCEST agent DO3AM-MPP with potential for receptor imaging: Synthesis, physico-chemical and MR studies;Bioorganic Chemistry;2021-01

3. New Trends and Current Status of Positron-Emission Tomography and Single-Photon-Emission Computerized Tomography Radioligands for Neuronal Serotonin Receptors and Serotonin Transporter;Bioconjugate Chemistry;2017-10-13

4. Mapping neuroreceptors with metal-labeled radiopharmaceuticals;MedChemComm;2017

5. Biotinidase Resistant 68Gallium-Radioligand Based on Biotin/Avidin Interaction for Pretargeting: Synthesis and Preclinical Evaluation;Bioconjugate Chemistry;2016-10-21