Insights into the RNA binding mechanism of human L1-ORF1p: a molecular dynamics study

Author:

Rajagopalan Muthukumaran1234,Balasubramanian Sangeetha1234ORCID,Ramaswamy Amutha1234ORCID

Affiliation:

1. Centre for Bioinformatics

2. School of Life Sciences

3. Pondicherry University

4. India

Abstract

The single-standard L1 mRNA binding pathway of ORF1p proposed by ligand mapping methodology and molecular dynamics simulations.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Reference64 articles.

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2. Hot L1s account for the bulk of retrotransposition in the human population

3. A. E. Hulme , D. A.Kulpa, J. L. G.Perez and J. V.Moran, in Genomic Disorders: The Genomic Basis of Disease, ed. J. R. Lupski and P. Stankiewicz, Humana Press, Totowa, NJ, 2006, pp. 35–55

4. LINE-mediated retrotransposition of marked Alu sequences

5. L1-mediated Retrotransposition of Murine B1 and B2 SINEs Recapitulated in Cultured Cells

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