(Z)-Selective anti-Markovnikov or Markovnikov thiol–yne-click reactions of an internal alkyne by amide hydrogen bond control

Author:

Pramanik Milan12345ORCID,Choudhuri Khokan12345ORCID,Chakraborty Subhayan12345ORCID,Ghosh Arindam12345ORCID,Mal Prasenjit12345ORCID

Affiliation:

1. School of Chemical Sciences

2. National Institute of Science Education and Research (NISER)

3. HBNI, Bhubaneswar

4. District Khurda

5. India

Abstract

Hydrogen bonding interactions like N–H⋯S, N–H⋯N and C–H⋯O helped to obtain either (Z)-selective anti-Markovnikov or Markovnikov Thiol–Yne-Click products exclusively with excellent yields from an internal alkyne under metal free conditions.

Funder

Council of Scientific and Industrial Research, India

National Institute of Science Education and Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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