Chelating silica nanoparticles for efficient antibiotic delivery and particle imaging in Gram-negative bacteria-Reference-Cited by-同舟云学术

Chelating silica nanoparticles for efficient antibiotic delivery and particle imaging in Gram-negative bacteria

Published:2023 Issue:9 Volume:5 Page:2453-2461
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Muguruza Asier R.¹^ORCID,di Maio Alessandro²^ORCID,Hodges Nikolas J.³^ORCID,Blair Jessica M. A.⁴^ORCID,Pikramenou Zoe¹^ORCID

Affiliation:

1. School of Chemistry, College of Engineering and Physical Sciences, University of Birmingham, Edgbaston, B15 2TT, UK

2. Birmingham Advanced Light Microscopy Facility, University of Birmingham, Edgbaston, B15 2TT, UK

3. School of Biosciences, University of Birmingham, Edgbaston, B15 2TT, UK

4. Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, B15 2TT, UK

Abstract

Silica nanoparticles decorated with aminocarboxylate ligands are novel vehicles to deliver antibiotics which are otherwise not able to penetrate the bacteria membrane and can also include agents for tracking and imaging.

Funder

Biotechnology and Biological Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NA/D2NA00884J

Reference31 articles.

1. Pathogenic Escherichia coli

2. Molecular mechanisms of antibiotic resistance

3. Permeability Barrier of Gram-Negative Cell Envelopes and Approaches To Bypass It

4. Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections

5. Mesoporous Silica and Organosilica Nanoparticles: Physical Chemistry, Biosafety, Delivery Strategies, and Biomedical Applications

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