Synthesis, anti-mycobacterial and cytotoxic evaluation of substituted isoindoline-1,3-dione-4-aminoquinolines coupled via alkyl/amide linkers

Author:

Rani Anu1234,Viljoen Albertus5678,Johansen Matt D.5678,Kremer Laurent56789,Kumar Vipan1234ORCID

Affiliation:

1. Department of Chemistry

2. Guru Nanak Dev University

3. Amritsar-143005

4. India

5. Institut de Recherche en Infectiologie (IRIM) de Montpellier

6. CNRS

7. UMR 9004 Université de Montpellier

8. France

9. INSERM

Abstract

A series of secondary amine-substituted isoindoline-1,3-dione-4-aminoquinolines were prepared via microwave heating and assayed for their anti-mycobacterial activities.

Funder

Council for Scientific and Industrial Research

Fondation pour la Recherche Médicale

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference34 articles.

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3. Revised National Tuberculosis Control Program , Training manual on intensified TB/HIV package , Ministry of Health and Family Welfare , New Delhi , 2017

4. Pyrazolo[1,5-a]pyridine-3-carboxamide hybrids: Design, synthesis and evaluation of anti-tubercular activity

5. WHO Multidrug and extensively drug-resistant TB 2010 Global report on surveillance and response ( http://www.apps.who.int/iris/bitstream/10665/44286/1/9789241599191_eng.pdf )

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