Comparative evaluation of 99mTc-MBIP-X/11[C] MBMP for visualization of 18 kDa translocator protein-Reference-Cited by-同舟云学术

Comparative evaluation of 99mTc-MBIP-X/11[C] MBMP for visualization of 18 kDa translocator protein

Published:2019 Issue:28 Volume:43 Page:11288-11295
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Srivastava Pooja¹²³⁴⁵,Kumari Neelam¹²³⁴,Kakkar Dipti¹²³⁴,Kaul Ankur¹²³⁴,Kumar Pravir⁵⁶⁷⁸⁴^ORCID,Tiwari Anjani K.¹²³⁴⁹^ORCID

Affiliation:

1. Division of Cyclotron and Radiopharmaceutical Sciences

2. Institute of Nuclear Medicine and Allied Sciences

3. Delhi 110054

4. India

5. Molecular Neuroscience and Functional Genomics Laboratory

6. Department of Biotechnology

7. Delhi Technological University

8. Delhi 110042

9. Department of Chemistry

Abstract

An elevated translocator protein (18 kDa, TSPO) density is observed during inflammation in the brain and peripheral organs making it a viable target for imaging.

Funder

Institute of Nuclear Medicine and Allied Sciences, Defence Research and Development Organisation

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ00180H

Reference32 articles.

1. The Translocator Protein 18 kDa (TSPO) and Its Role in Mitochondrial Biology and Psychiatric Disorders

2. TSPO as a target for treatments of diseases, including neuropathological disorders

3. Translocator protein 18 kDa (TSPO): Molecular sensor of brain injury and repair

4. Regulation of translocator protein 18kDa (TSPO) expression in health and disease states☆

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