Computational studies and synthesis of <sup>131</sup>iodine-labeled nocardiotide A analogs as a peptide-based theragnostic radiopharmaceutical ligand for cancer targeting SSTR2-Reference-Cited by-同舟云学术

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Computational studies and synthesis of ¹³¹iodine-labeled nocardiotide A analogs as a peptide-based theragnostic radiopharmaceutical ligand for cancer targeting SSTR2

Published:2024 Issue:16 Volume:14 Page:10962-10968
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sugiharti Rizky Juwita¹²,Maharani Rani³^ORCID,Kurniawan Fransiska¹^ORCID,Kartasasmita Rahmana Emran¹,Tjahjono Daryono Hadi¹^ORCID

Affiliation:

1. School of Pharmacy, Bandung Institute of Technology, Bandung, Indonesia

2. Research Center for Radioisotope, Radiopharmaceutical, and Biodosimetry Technology, National Research and Innovation Agency, Indonesia

3. Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor, Indonesia

Abstract

The cWIWLYA peptide shows high labeling efficiency with I-131 (>90%). Its 131I2-complex has high stability at room temperature as well as in plasma.

Funder

Institut Teknologi Bandung

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA00684D

Reference27 articles.

1. Radiolabeled Peptides: Valuable Tools for the Detection and Treatment of Cancer

2. Radiolabeled Peptides and Antibodies in Medicine

3. Radiopharmaceuticals for somatostatin receptor imaging

4. Overview of Radiolabeled Somatostatin Analogs for Cancer Imaging and Therapy

5. Peptide-Drug Conjugates and Their Targets in Advanced Cancer Therapies

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