Lipid composition: a “key factor” for the rational manipulation of the liposome–protein corona by liposome design-Reference-Cited by-同舟云学术

Lipid composition: a “key factor” for the rational manipulation of the liposome–protein corona by liposome design

Published:2015 Issue:8 Volume:5 Page:5967-5975
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Caracciolo G.¹²³⁴,Pozzi D.¹²³⁴,Capriotti A. L.⁵²⁶⁴,Cavaliere C.⁵²⁶⁴,Piovesana S.⁵²⁶⁴,Amenitsch H.⁷⁸⁹¹⁰,Laganà A.⁵²⁶⁴

Affiliation:

1. Department of Molecular Medicine

2. ‘Sapienza’ University of Rome

3. 00161 Rome

4. Italy

5. Department of Cheimistry

6. 00185 Rome

7. Institute of inorganic Chemistry

8. Graz University of Technology

9. 8010 Graz

10. Austria

Abstract

When liposomes are exposed to biological fluids, a dynamic protein coating immediately covers them forming a ‘protein corona’. Those proteins can interact with receptors (over)expressed on the plasma membrane of target cells bringing the liposomes to their final destination.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA13335H

Reference43 articles.

1. Development of liposomal formulations: From concept to clinical investigations

2. pH-sensitive liposomes for drug delivery in cancer treatment

3. Doxil® — The first FDA-approved nano-drug: Lessons learned

4. Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles

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