A novel polymeric micelle-decorated Fe3O4/Au core–shell nanoparticle for pH and reduction-responsive intracellular co-delivery of doxorubicin and 6-mercaptopurine

Author:

Ghorbani Marjan1234ORCID,Mahmoodzadeh Farideh5674,Nezhad-Mokhtari Parinaz8234,Hamishehkar Hamed9234ORCID

Affiliation:

1. Stem Cell Research Center

2. Tabriz University of Medical Sciences

3. Tabriz

4. Iran

5. Halal Research Center of IRI

6. FDA

7. Tehran

8. Biotechnology Research Center

9. Drug Applied Research Center

Abstract

The synergistic antitumor activity against MCF-7 cells was confirmed by co-delivery of doxorubicin and 6-mercaptopurine via dual pH/reduction-responsive nanoparticles.

Funder

Drug Applied Research Center, Tabriz University of Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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