New synthetic pathways to the Anastrepha ludens host marking pheromone: harnessing iridium-catalysis with novel P,N-ligand for enantioselective construction

Author:

Pawar Tushar Janardan1ORCID,Barcelona-Cazanave Liliette1,Bonilla-Landa Israel1,Escobar Magdalena2,Jimenez-Halla J. Oscar C.3,Altúzar-Molina Alma4,Romero-Arellano Patricia1,Edmunds Andrew J. F.5,Aluja Martín4,Olivares-Romero José Luis1ORCID

Affiliation:

1. Red de Estudios Moleculares Avanzados, Clúster Científico y Tecnológico BioMimic®, Instituto de Ecología, A.C. – INECOL, Carretera antigua a Coatepec 351, El Haya, Xalapa 91073, Veracruz, Mexico

2. Insituto de Química Aplicada, Universidad Veracruzana, Veracruz, Mexico

3. Departamento de Química, División de Ciencias Naturales y Exactas, Universidad de Guanajuato, Noria Alta S/N, 36050, Guanajuato, Mexico

4. Red de Manejo Bioracional de Plagas y Vectores, Clúster Científico y Tecnológico BioMimic®, Instituto de Ecología, A.C. – INECOL, Carretera antigua a Coatepec 351, El Haya, Xalapa 91073, Veracruz, Mexico

5. Syngenta Crop Protection, AG Schaffhauserstrasse, CH-4332 Stein, Switzerland

Abstract

A highly efficient iridium-catalyzed asymmetric hydrogenation approach is described for the total synthesis of the biologically active (R,L) A. ludens host marking pheromone (HMP).

Funder

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference47 articles.

1. Pioneering Perspectives on Asymmetric Hydrogenation†

2. J. G.de Vries and C. J.Elsevier , Handbook of Homogeneous Hydrogenation , Wiley-VCH , Weinheim , 2007

3. H.-U.Blaser and E.Schmidt , Asymmetric Catalysis on Industrial Scale: Challenges, Approaches, and Solutions , Wiley-VCH , Weinheim , 2004

4. New Chiral Phosphorus Ligands for Enantioselective Hydrogenation

5. E. J.Corey and L.Kürti , Enantioselective Chemical Synthesis: Methods, logic, and practice , Direct Book Publishing , 2010

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