Understanding the effects of ethanol on the liposome bilayer structure using microfluidic-based time-resolved small-angle X-ray scattering and molecular dynamics simulations-Reference-Cited by-同舟云学术

Understanding the effects of ethanol on the liposome bilayer structure using microfluidic-based time-resolved small-angle X-ray scattering and molecular dynamics simulations

Published:2024 Issue:8 Volume:6 Page:2166-2176
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Maeki Masatoshi¹²³^ORCID,Kimura Niko⁴,Okada Yuto⁴,Shimizu Kazuki⁴,Shibata Kana⁵,Miyazaki Yusuke⁶,Ishida Akihiko¹^ORCID,Yonezawa Kento³,Shimizu Nobutaka³,Shinoda Wataru⁶^ORCID,Tokeshi Manabu¹^ORCID

Affiliation:

1. Division of Applied Chemistry, Faculty of Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, Sapporo 060-8628, Japan

2. JST PRESTO, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan

3. Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki 305-0801, Japan

4. Graduate School of Chemical Sciences and Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, Sapporo 060-8628, Japan

5. Department of Materials Chemistry, Nagoya University, Chikusa-ku, Nagoya 464-8603, Japan

6. Research Institute for Interdisciplinary Science, Okayama University, Okayama 700-8530, Japan

Abstract

We investigated ethanol-induced structural changes in liposomes on a time scale from microseconds to tens of seconds using a microfluidic-based small-angle X-ray scattering (SAXS) measurement system coupled with molecular dynamics (MD) simulations.

Funder

Core Research for Evolutional Science and Technology

Hokkaido University

Ministry of Education, Culture, Sports, Science and Technology

Precursory Research for Embryonic Science and Technology

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Japan Science and Technology Agency

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NA/D3NA01073B