Controlling the self-assembly of human calcitonin: a theoretical approach using molecular dynamics simulations-Reference-Cited by-同舟云学术

Controlling the self-assembly of human calcitonin: a theoretical approach using molecular dynamics simulations

Published:2021 Issue:26 Volume:23 Page:14496-14510
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Paul Srijita¹²³⁴,Paul Sandip¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Indian Institute of Technology Guwahati

3. Guwahati

4. India

Abstract

We study the amyloidogenic behavior of human calcitonin (hCT) and its peptide based derivatives i.e., sCT, phCT, N17H hCT, Y12L hCT and DM hCT, through classical molecular dynamics simulations.

Funder

Indian Institute of Technology Guwahati

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CP/D1CP00825K

Reference57 articles.

1. Calcitonin alters behaviour of isolated osteoclasts

2. THE EFFECTS OF PARATHYROID HORMONE, COLCHICINE, AND CALCITONIN ON THE ULTRASTRUCTURE AND THE ACTIVITY OF OSTEOCLASTS IN ORGAN CULTURE

3. Calcitonin

4. EFFECTS OF CALCITONIN ON PATIENTS WITH PAGET'S DISEASE, THYROTOXICOSIS, OR HYPERCALCÆMIA

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