Protective effect of 1,3-dioleoyl-2-palmitoylglycerol against DSS-induced colitis <i>via</i> modulating gut microbiota and maintaining intestinal epithelial barrier integrity-Reference-Cited by-同舟云学术

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Protective effect of 1,3-dioleoyl-2-palmitoylglycerol against DSS-induced colitis via modulating gut microbiota and maintaining intestinal epithelial barrier integrity

Published:2024 Issue:17 Volume:15 Page:8700-8711
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Li Wusun¹,Tang Xiaoyan¹^ORCID,Liu Hui¹,Liu Ke¹,Tian Zhiqing¹,Zhao Yujie¹

Affiliation:

1. Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standards & Testing Technology for Agro-Products of Chinese Academy of Agricultural Sciences, Beijing 100081, China

Abstract

A schematic diagram illustrates how OPO protects against DSS-induced colitis by modulating gut microbiota, enhancing intestinal epithelial barrier integrity, and subsequently downregulating the TLR4-MyD88-NF-κB signaling pathway.

Funder

Chinese Academy of Agricultural Sciences

Agriculture Research System of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO02344G

Reference44 articles.

1. The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

2. Current insights on the roles of gut microbiota in inflammatory bowel disease-associated extra-intestinal manifestations: pathophysiology and therapeutic targets

3. Intestinal barriers protect against disease

4. Tales from the crypt: new insights into intestinal stem cells

5. Paracellular permeability and tight junction regulation in gut health and disease

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