BF<sub>3</sub>·OEt<sub>2</sub>-mediated transamidation of unprotected primary amides under solvent-free conditions-Reference-Cited by-同舟云学术

BF₃·OEt₂-mediated transamidation of unprotected primary amides under solvent-free conditions

Published:2024 Issue:32 Volume:22 Page:6605-6611
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Gui Qing-Wen¹^ORCID,Ying Shengneng¹,Liu Xin¹,Wang Jianfang²^ORCID,Xiao Xuliang¹,Liu Zhuoliang²,Wang Xia¹,Shang Yanxue¹,Li Qiang³

Affiliation:

1. College of Chemistry and Materials Science, Hunan Agricultural University, Changsha, Hunan 410128, People's Republic of China

2. College of Science, National University of Defense Technology, Changsha 410128, People's Republic of China

3. College of Agronomy, Hunan Agricultural University, Changsha 410128, People's Republic of China

Abstract

Here, we developed a novel Lewis acid BF3·OEt2-promoted transamidation method. In this work, both primary and secondary amines can undergo transamidation, and achieve excellent chemoselectivity and atom economy.

Funder

Hunan Provincial Science and Technology Department

China Postdoctoral Science Foundation

Natural Science Foundation of Hunan Province

Education Department of Hunan Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00875H

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