Rapid cell pairing and fusion based on oscillating bubbles within an acoustofluidic device-Reference-Cited by-同舟云学术

Rapid cell pairing and fusion based on oscillating bubbles within an acoustofluidic device

Published:2022 Issue:5 Volume:22 Page:921-927
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Liu Xiufang¹²,Zhang Wenjun²,Farooq Umar²,Rong Ning²,Shi Jingyao²,Pang Na¹²,Xu Lisheng¹,Niu Lili²,Meng Long²^ORCID

Affiliation:

1. College of Medicine and Biological information engineering, Northeastern University, Liaoning 110819, China

2. Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Guangdong 518055, China

Abstract

An acoustofluidic device based on oscillating bubbles was designed to rapidly pair and fuse cells with no limitation of cell size. The cell pairing rate reached 90% within 40 ms and fused cells kept biological functions.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D1LC01074C

Reference45 articles.

1. On chip electrofusion of single human B cells and mouse myeloma cells for efficient hybridoma generation

2. Hybridoma technologies for antibody production