The main anthocyanin monomer of Lycium ruthenicum Murray induces apoptosis through the ROS/PTEN/PI3K/Akt/caspase 3 signaling pathway in prostate cancer DU-145 cells

Author:

Li Zhan-Long1234,Mi Jia5674,Lu Lu5674,Luo Qing5674,Liu Xi1234,Yan Ya-Mei5674,Jin Bo5674,Cao You-Long5674,Zeng Xiao-Xiong89104ORCID,Ran Lin-Wu123411ORCID

Affiliation:

1. College of Public Health and Management

2. Ningxia Medical University

3. Yinchuan 750004

4. China

5. Institute of Wolfberry Engineering Technology

6. Ningxia Academy of Agriculture and Forestry Sciences

7. Yinchuan 750002

8. College of Food Science and Technology

9. Nanjing Agricultural University

10. Nanjing 210095

11. Laboratory Animal Center

Abstract

Pt3G inhibits DU-145 cell proliferation and induces apoptosis through the ROS/PTEN/PI3K/Akt/caspase-3 signaling pathway.

Funder

National Natural Science Foundation of China

Key Research and Development Program of Ningxia

Natural Science Foundation of Ningxia Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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