Development of a peptide-based lateral flow assay for the detection of the cancer biomarker Mdm2-Reference-Cited by-同舟云学术

Development of a peptide-based lateral flow assay for the detection of the cancer biomarker Mdm2

Published:2024 Issue: Volume: Page:
ISSN:2635-0998
Container-title:Sensors & Diagnostics
language:en
Short-container-title:Sens. Diagn.

Author:

Gosselin Bryan¹²,Retout Maurice¹^ORCID,Jabin Ivan²^ORCID,Bruylants Gilles¹^ORCID

Affiliation:

1. Engineering of Molecular NanoSystems, Ecole Polytechnique de Bruxelles, Université Libre de Bruxelles (ULB), Avenue F. D. Roosevelt 50, CP165/64, B-1050 Brussels, Belgium

2. Laboratoire de Chimie Organique, Université Libre de Bruxelles (ULB), Avenue F. D. Roosevelt 50, CP160/06, B-1050 Brussels, Belgium

Abstract

This study explores the use of peptide aptamers as effective recognition units in lateral flow assays, comparing two immobilization strategies on test line. Peptide aptamers show superior performance and ease of use compared to classical antibodies.

Funder

Fonds pour la Formation à la Recherche dans l’Industrie et dans l’Agriculture

Fédération Wallonie-Bruxelles

Fonds Alice et David van Buuren

Université libre de Bruxelles

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SD/D3SD00253E

Reference38 articles.

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