Rod-shaped and fluorine-substituted hydroxyapatite free of molecular immunopotentiators stimulates anti-cancer immunity in vivo-Reference-Cited by-同舟云学术

Rod-shaped and fluorine-substituted hydroxyapatite free of molecular immunopotentiators stimulates anti-cancer immunity in vivo

Published:2016 Issue:44 Volume:52 Page:7078-7081
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Wang Xiupeng¹²³⁴⁵,Li Xia¹²³⁴⁵,Ito Atsuo¹²³⁴⁵,Watanabe Yohei⁶⁷²³⁴,Tsuji Noriko M.⁶⁷²³⁴

Affiliation:

1. Health Research Institute

2. Department of Life Science and Biotechnology

3. National Institute of Advanced Industrial Science and Technology (AIST)

4. Tsukuba

5. Japan

6. Immune Homeostasis Lab.

7. Biomedical Research Institute

Abstract

Rod-shaped and fluorine-substituted hydroxyapatite nanoparticles significantly increased the cellular uptake of a model antigen by BMDCs, improved antigen presentation, stimulated immune-related cytokine secretion, and enhanced the anti-cancer immunity.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC02848A

Reference31 articles.

1. Towards an understanding of the adjuvant action of aluminium

2. Stimulation of In Vivo Antitumor Immunity with Hollow Mesoporous Silica Nanospheres

3. Comprehensive Mechanism Analysis of Mesoporous-Silica-Nanoparticle-Induced Cancer Immunotherapy

4. Vaccinology at the beginning of the 21st century

5. Particle-size-dependent toxicity and immunogenic activity of mesoporous silica-based adjuvants for tumor immunotherapy

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