Rod-shaped and fluorine-substituted hydroxyapatite free of molecular immunopotentiators stimulates anti-cancer immunity in vivo
Author:
Affiliation:
1. Health Research Institute
2. Department of Life Science and Biotechnology
3. National Institute of Advanced Industrial Science and Technology (AIST)
4. Tsukuba
5. Japan
6. Immune Homeostasis Lab.
7. Biomedical Research Institute
Abstract
Rod-shaped and fluorine-substituted hydroxyapatite nanoparticles significantly increased the cellular uptake of a model antigen by BMDCs, improved antigen presentation, stimulated immune-related cytokine secretion, and enhanced the anti-cancer immunity.
Funder
Japan Society for the Promotion of Science
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2016/CC/C6CC02848A
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