Base excision repair mediated cascading triple-signal amplification for the sensitive detection of human alkyladenine DNA glycosylase-Reference-Cited by-同舟云学术

Base excision repair mediated cascading triple-signal amplification for the sensitive detection of human alkyladenine DNA glycosylase

Published:2019 Issue:9 Volume:144 Page:3064-3071
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Zhang Huige¹²³⁴⁵,Wang Lili¹²³⁴⁵,Xie Yi⁶³⁴⁵,Zuo Xianwei⁷⁸⁴⁵,Chen Hongli¹²³⁴⁵^ORCID,Chen Xingguo¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Applied Organic Chemistry

2. College of Chemistry and Chemical Engineering

3. Lanzhou University

4. Lanzhou 730000

5. China

6. School of Life Sciences

7. Key Laboratory of Sensor and Sensing Technology of Gansu Province

8. Gansu Academy of Sciences

Abstract

DNA glycosylase (DG) plays a significant role in repairing DNA lesions, and the dysregulation of DG activity is associated with a variety of human pathologies.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/AN/C9AN00200F

Reference37 articles.

1. In vivo measurements of interindividual differences in DNA glycosylases and APE1 activities

2. Genome maintenance mechanisms for preventing cancer

3. Catalytic Promiscuity and the Divergent Evolution of DNA Repair Enzymes

4. The mechanics of base excision repair, and its relationship to aging and disease

5. hOGG1Ser326Cys polymorphism is associated with risk of bladder cancer in a Chinese population: A case-control study

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