Exploring the impact of trifluoromethyl (–CF<sub>3</sub>) functional group on the anti-cancer activity of isoxazole-based molecules: design, synthesis, biological evaluation and molecular docking analysis-Reference-Cited by-同舟云学术

Exploring the impact of trifluoromethyl (–CF₃) functional group on the anti-cancer activity of isoxazole-based molecules: design, synthesis, biological evaluation and molecular docking analysis

Published:2024 Issue:27 Volume:14 Page:18856-18870
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Pattanayak Paramita¹^ORCID,Nikhitha Sripathi²^ORCID,Halder Debojyoti²^ORCID,Ghosh Balaram²^ORCID,Chatterjee Tanmay¹^ORCID

Affiliation:

1. Department of Chemistry, Birla Institute of Technology and Science, Pilani (BITS Pilani), Hyderabad Campus, Jawahar Nagar, Hyderabad 500078, Telangana, India

2. Epigenetic Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani (BITS Pilani), Hyderabad Campus, Jawahar Nagar, Hyderabad 500078, Telangana, India

Abstract

The effect of –CF3 functional group on the enhancement of anti-breast cancer activity of isoxazole based molecules against MCF-7 is demonstrated.

Funder

Indian Council of Medical Research

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Department of Health Research, India

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA02856B

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