Olive leaf extract counteracts cell proliferation and cyst growth in an in vitro model of autosomal dominant polycystic kidney disease
Author:
Affiliation:
1. Kidney and Transplantation Research Center Annunziata Hospital
2. Cosenza
3. Italy
4. Department DiBEST
5. Unit of Biochemistry and Molecular Biotechnology
6. University of Calabria
7. Department of Pharmacy
8. Health and Nutritional Sciences
Abstract
–Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive enlargement of kidney cysts, leading to chronic kidney disease.
Funder
Fondazione Cassa di Risparmio di Calabria e Lucania
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2018/FO/C8FO01481G
Reference51 articles.
1. Polycystic Kidney Disease
2. Genetic Heterogeneity of Polycystic Kidney Disease in Europe1
3. Calcium Restriction Allows cAMP Activation of the B-Raf/ERK Pathway, Switching Cells to a cAMP-dependent Growth-stimulated Phenotype
4. Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease
5. Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease
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1. Olea europaea L. Leaf Extract Alleviates Fibrosis Progression and Oxidative Stress Induced by Bleomycin on a Murine Model of Lung Fibrosis;Dose-Response;2023-07
2. Plant-derived compounds for treating autosomal dominant polycystic kidney disease;Frontiers in Nephrology;2023-02-03
3. Health benefits of olive oil and by-products and possible innovative applications for industrial processes;Functional Foods in Health and Disease;2021-07-16
4. Olive Leaf Extract (OLE) impaired vasopressin-induced aquaporin-2 trafficking through the activation of the calcium-sensing receptor;Scientific Reports;2021-02-25
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