Contra-thermodynamic halolactonization of lactam-tethered 5-aryl-4(<i>E</i>)-pentenoic acids for the flexible and stereocontrolled synthesis of fused lactam-halolactones-Reference-Cited by-同舟云学术

Contra-thermodynamic halolactonization of lactam-tethered 5-aryl-4(E)-pentenoic acids for the flexible and stereocontrolled synthesis of fused lactam-halolactones

Published:2022 Issue:44 Volume:12 Page:28685-28691
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Beng Timothy K.¹^ORCID,Borg Claire¹,Rodriguez Morgan J.¹

Affiliation:

1. Department of Chemistry, Central Washington University, Ellensburg, WA 98926, USA

Abstract

The contra-thermodynamic halolactonization of lactam-tethered 5-aryl-4(E)-pentenoic acids, under solvent- and catalyst-controlled conditions, has facilitated the efficient and stereocontrolled synthesis of halogenated fused γ-lactone-lactams.

Funder

Central Washington University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA04177D

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