Design and virtual screening of novel fluoroquinolone analogs as effective mutant DNA GyrA inhibitors against urinary tract infection-causing fluoroquinolone resistant Escherichia coli-Reference-Cited by-同舟云学术

Design and virtual screening of novel fluoroquinolone analogs as effective mutant DNA GyrA inhibitors against urinary tract infection-causing fluoroquinolone resistant Escherichia coli

Published:2018 Issue:42 Volume:8 Page:23629-23647
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Balasubramaniyan Sakthivel¹²³⁴⁵^ORCID,Irfan Navabshan¹²³⁴⁵^ORCID,Umamaheswari Appavoo¹²³⁴⁵^ORCID,Puratchikody Ayarivan¹²³⁴⁵^ORCID

Affiliation:

1. Drug Discovery and Development Research Group

2. Department of Pharmaceutical Technology

3. University College of Engineering

4. Anna University

5. Tiruchirapalli-62024

Abstract

Design and development of novel fluoroquinolones analogs using target (mutant DNA GyrA), ligand-based SAR and virtual screening techniques.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA01854E

Reference40 articles.

1. Immunity to uropathogens: the emerging roles of inflammasomes

2. Determinants of quinolone resistance in Escherichia coli causing community-acquired urinary tract infection in Bejaia, Algeria

3. Suppression of gyrase-mediated resistance by C7 aryl fluoroquinolones

4. gyrA Mutations in high-level fluoroquinolone-resistant clinical isolates of Escherichia coli

5. Fluoroquinolone Resistance Among Gram-Negative Urinary Tract Patho-gens: Global Smart Program Results, 2009-2010

Cited by 18 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Effect of co-pigments on anthocyanins of Rhododendron arboreum and insights into interaction mechanism;Food Chemistry;2023-11

2. A Perspective into “TEL”-Tenofovir, Emtricitabine and Lamivudine Antileprotic Activities by Drug Repurposing and Exploring the Possibility of Combination Chemotherapy with Drug Rescued Molecules for a Leprosy Free Mankind;Recent Advances in Anti-Infective Drug Discovery;2023-11

3. Multi-step synthesis of novel 2-methyl-3-carboxamide-4-quinolones and an enhanced sampling simulation method to identify potentiators for cystic fibrosis;Materials Today Chemistry;2023-10

4. Quinoline analogue as a potential inhibitor of SARS-CoV-2 main protease: ADMET prediction, molecular docking and dynamics simulation analysis;European Journal of Chemistry;2023-03-31

5. Design, Synthesis, Characterization of Novel Sulfathiazole Derivatives and their in silico and in vitro Analysis against Multidrug-Resistance Tuberculosis using Docking Studies;Asian Journal of Chemistry;2022-12-27