Visible-light-promoted radical cascade alkylation/cyclization: access to alkylated indolo/benzoimidazo[2,1-<i>a</i>]isoquinolin-6(5<i>H</i>)-ones-Reference-Cited by-同舟云学术

Visible-light-promoted radical cascade alkylation/cyclization: access to alkylated indolo/benzoimidazo[2,1-a]isoquinolin-6(5H)-ones

Published:2022 Issue:48 Volume:20 Page:9659-9671
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Yu Wen-Qin¹,Xiong Bi-Quan¹^ORCID,Zhong Long-Jin¹,Liu Yu¹^ORCID

Affiliation:

1. Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang 414006, China

Abstract

A visible-light-promoted alkylation/cyclization of active alkenes via radical cascade cyclization for the preparation of functionalized isoquinolinones by using Hantzsch esters as alkylation radical precursors.

Funder

Scientific Research Foundation of Hunan Provincial Education Department

Science and Technology Program of Hunan Province

Natural Science Foundation ofHunan Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB01732F

Reference126 articles.

1. Indolo[2,1-a]isoquinolines. Syntheses, steroid hormone receptor binding affinities, and cytostatic activity

2. Inhibition of Tubulin Polymerization by 5,6-Dihydroindolo[2,1-a]isoquinoline Derivatives

3. Reduced Benzimidazo[2,1-a]isoquinolines. Synthesis and Cytotoxicity Studies

4. Synthesis and toxicity towards normal and cancer cell lines of benzimidazolequinones containing fused aromatic rings and 2-aromatic ring substituents

5. Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells

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