Catalytic enantioselective synthesis of tetrasubstituted chromanones via palladium-catalyzed asymmetric conjugate arylation using chiral pyridine-dihydroisoquinoline ligands

Author:

Baek Doohyun1234ORCID,Ryu Huijeong1234ORCID,Ryu Ji Yeon1564,Lee Junseong1564ORCID,Stoltz Brian M.7891011ORCID,Hong Sukwon123412ORCID

Affiliation:

1. Department of Chemistry

2. Gwangju Institute of Science and Technology

3. Gwangju 61005

4. Republic of Korea

5. Chonnam National University

6. Gwangju 61186

7. The Warren and Katharine Schlinger Laboratory of Chemistry and Chemical Engineering

8. Division of Chemistry and Chemical Engineering

9. California Institute of Technology

10. Pasadena

11. USA

12. School of Materials Science and Engineering

Abstract

The first palladium-catalyzed enantioselective conjugate addition reactions of arylboronic acids to 2-substituted chromones with chiral pyridine-dihydroisoquinoline ligands have been developed.

Funder

National Institute of General Medical Sciences

National Research Foundation of Korea

Gwangju Institute of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference63 articles.

1. L. C. Chang and A. D.Kinghorn , Bioactive compounds from natural sources: isolation, characterization and biological properties , Taylor & Francis , London , 2001

2. R. J. Grayer and N. C.Veitch , Flavonoids: Chemistry, Biochemistry and Applications , CRC, Taylor & Francis , Boca Raton, FL , 2006

3. Recent advances of chroman-4-one derivatives: Synthetic approaches and bioactivities

4. Antimicrobial 3-methylene flavanones

5. A. E. Nibbs and K. A.Scheidt , Eur. J. Org. Chem. , 2012 , 449462

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3