A carboxymethyl chitosan and peptide-decorated polyetheretherketone ternary biocomposite with enhanced antibacterial activity and osseointegration as orthopedic/dental implants

Author:

Xu Anxiu12345,Zhou Liwei6785,Deng Yi9103115,Chen Xianshen6785,Xiong Xiaoling12345,Deng Feng1213145,Wei Shicheng12345

Affiliation:

1. The 2nd Dental Center and Central Laboaratory

2. School and Hospital of Stomatology

3. Peking University

4. Beijing 100081

5. China

6. Department of Stomatology

7. Shenzhen Maternity & Child Healthcare Hospital

8. Shenzhen

9. Center for Biomedical Materials and Tissue Engineering

10. Academy for Advanced Interdisciplinary Studies

11. Beijing 100871

12. Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences

13. Chongqing Medical University

14. Chongqing 401147

Abstract

A carboxymethyl chitosan and peptide-decorated PEEK ternary biocomposite showed enhanced antibacterial activity, in vitro osteogenic differentiation and in vivo osseointegration.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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