Facilely synthesized pH-responsive fluorescent polymer dots entrapping doped and coupled doxorubicin for nucleus-targeted chemotherapy-Reference-Cited by-同舟云学术

Facilely synthesized pH-responsive fluorescent polymer dots entrapping doped and coupled doxorubicin for nucleus-targeted chemotherapy

Published:2017 Issue:16 Volume:5 Page:2921-2930
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Guo Yixiao¹²³⁴,Cao Fengwen¹²³⁴,Li Yao¹²³⁴,Xiong Liqin¹²³⁴⁵^ORCID

Affiliation:

1. Shanghai Med-X Engineering Research Center, School of Biomedical Engineering

2. Shanghai Jiao Tong University

3. Shanghai 200030

4. P. R. China

5. Department of Nuclear Medicine, Rui Jin Hospital

Abstract

The combination of physical doping and chemical coupling can significantly enhance the drug loading/release efficiency and improve the effect of cancer treatment. Based on this strategy, PEG-Dox doped and coupled PFBT polymer dots were optimized as a nucleus-targeted drug delivery platform for tumor therapy.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C7TB00394C

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