Deoxygenative arylation of secondary amides by merging iridium catalysis with electrochemical radical cross-coupling-Reference-Cited by-同舟云学术

Deoxygenative arylation of secondary amides by merging iridium catalysis with electrochemical radical cross-coupling

Published:2023 Issue:22 Volume:25 Page:9080-9085
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Li Jingan¹²,He Youliang²,Jiang Feng²,Wang Xiaoming¹²^ORCID

Affiliation:

1. School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, 1 Sub-lane Xiangshan, Hangzhou 310024, China

2. State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China

Abstract

A deoxygenative arylation of amides using aromatic nitriles via merging Ir-catalyzed amide reduction with electrochemistry has been achieved, which may provide an alternative strategy for access to value-added amines from inert amides.

Funder

Natural Science Foundation of Ningbo

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/GC/D3GC03193D

Reference78 articles.

1. Review of Methods for the Catalytic Hydrogenation of Carboxamides

2. Increasing the Reactivity of Amides towards Organometallic Reagents: An Overview