Controlled release of anticancer drug Paclitaxel using nano-structured amphiphilic star-hyperbranched block copolymers

Author:

Geyik Caner12345,Ciftci Mustafa6785,Demir Bilal191045,Guler Bahar191045,Ozkaya A. Burak1111245,Gumus Z. Pınar12345,Barlas F. Baris191045,Odaci Demirkol Dilek191045,Coskunol Hakan12345,Timur Suna12345,Yagci Yusuf6785

Affiliation:

1. Ege University

2. Institute on Drug Abuse

3. Toxicology and Pharmaceutical Sciences

4. 35100, Izmir

5. Turkey

6. Istanbul Technical University

7. Department of Chemistry

8. 34469, Istanbul

9. Faculty of Science

10. Department of Biochemistry

11. School of Medicine

12. Department of Medical Biochemistry

Abstract

Two amphiphilic star-hyperbranched copolymers with different hydrophilic PHEMA segments were synthesized, and their drug loading/release profiles were examined by using Paclitaxel.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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