A sensitive isothermal fluorescence biosensor for microRNA detection coupling primer exchange reaction with catalytic hairpin assembly

Author:

Liu Jiatong1,Shen Minzhe1,Talap Jadera1,Shen Xudan1ORCID,Song Zihan1,Hu Haihong1,Zeng Su1,Cai Sheng1ORCID

Affiliation:

1. Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, Zhejiang University, Hangzhou, Zhejiang 310058, China

Abstract

A novel biosensor for sensitive detection of miRNAs was established based on coupling the primer exchange reaction (PER) with catalytic hairpin assembly (CHA).

Funder

Natural Science Foundation of Zhejiang Province

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

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