O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond
Author:
Affiliation:
1. Department of Molecular Biology and Biochemistry
2. Simon Fraser University
3. Burnaby, Canada
4. Department of Chemistry
Abstract
Increasing levels of glucose responsiveO-GlcNAcylation of proteins in Alzheimer disease mouse models decreases the toxicity of tau and Aβ.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/CS/C4CS00038B
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