Stain-free identification of tissue pathology using a generative adversarial network to infer nanomechanical signatures-Reference-Cited by-同舟云学术

Stain-free identification of tissue pathology using a generative adversarial network to infer nanomechanical signatures

Published:2021 Issue:22 Volume:3 Page:6403-6414
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Neary-Zajiczek Lydia¹²^ORCID,Essmann Clara²^ORCID,Rau Anita¹^ORCID,Bano Sophia¹^ORCID,Clancy Neil¹³^ORCID,Jansen Marnix⁴^ORCID,Heptinstall Lauren⁵,Miranda Elena⁶^ORCID,Gander Amir⁷^ORCID,Pawar Vijay²^ORCID,Fernandez-Reyes Delmiro²^ORCID,Shaw Michael¹²⁸^ORCID,Davidson Brian¹^ORCID,Stoyanov Danail¹^ORCID

Affiliation:

1. Wellcome/EPSRC Centre for Surgical and Interventional Sciences, London, W1W 7TS, UK

2. Department of Computer Science, University College London, London, WC1E 6BT, UK

3. Department of Medical Physics and Biomedical Engineering, University College London, London, WC1E 6BT, UK

4. Department of Pathology, UCL Cancer Institute, University College London, London, WC1E 6BT, UK

5. Department of Cellular Pathology, Royal Free Hospital, London, NW3 2QG, UK

6. Biobank and Pathology Translational Technology Platform, UCL Cancer Institute, University College London, London, WC1E 6BT, UK

7. Department of Surgical Biotechnology, University College London, London, WC1E 6BT, UK

8. National Physical Laboratory, Teddington, TW11 0LW, UK

Abstract

Sample-wide elastic modulus is inferred from unstained images of frozen liver tissue sections. Distribution parameters can predict tissue pathology for use as an intraoperative diagnostic tool.

Funder

Engineering and Physical Sciences Research Council

Wellcome

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NA/D1NA00527H

Reference57 articles.

1. Improved survival after resection of colorectal liver metastases

2. Intraoperative frozen section for identifying the invasion status of lung adenocarcinoma: A systematic review and meta-analysis

3. Immediate intraoperative sentinel lymph node analysis by frozen section is predictive of lymph node metastasis in endometrial cancer

4. Accuracy of intraoperative frozen section for the evaluation of ovarian neoplasms: an institutional experience

5. The Usefulness of Intraoperative Circumferential Frozen-Section Analysis of Lumpectomy Margins in Breast-Conserving Surgery