Methyltransferase-directed covalent coupling of fluorophores to DNA-Reference-Cited by-同舟云学术

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Methyltransferase-directed covalent coupling of fluorophores to DNA

Published:2017 Issue:5 Volume:8 Page:3804-3811
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Lauer Milena Helmer¹²³⁴⁵^ORCID,Vranken Charlotte¹²³⁴,Deen Jochem¹²³⁴^ORCID,Frederickx Wout¹²³⁴,Vanderlinden Willem¹²³⁴,Wand Nathaniel⁶⁷⁸⁹,Leen Volker¹²³⁴,Gehlen Marcelo H.⁵¹⁰¹¹,Hofkens Johan¹²³⁴^ORCID,Neely Robert K.⁶⁷⁸⁹^ORCID

Affiliation:

1. Department of Chemistry

2. KU Leuven

3. 3001 Heverlee

4. Belgium

5. Institute of Chemistry of São Carlos

6. School of Chemistry

7. University of Birmingham

8. Birmingham B15 2TT

9. UK

10. University of São Paulo

11. Brazil

Abstract

Highly efficient DNA labelling using an enzymatically-directed, strain-promoted azide–alkyne cycloaddition.

Funder

Vlaamse Overheid

Fonds Wetenschappelijk Onderzoek

European Research Council

Engineering and Physical Sciences Research Council

Agentschap voor Innovatie door Wetenschap en Technologie

Horizon 2020

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C6SC04229E

Reference27 articles.

1. A new tool for biotechnology: AdoMet-dependent methyltransferases

2. S-Adenosyl-Methionine-Dependent Methyltransferases: Highly Versatile Enzymes in Biocatalysis, Biosynthesis and Other Biotechnological Applications

3. SAM/SAH Analogs as Versatile Tools for SAM-Dependent Methyltransferases

4. Beyond Watson and Crick: DNA Methylation and Molecular Enzymology of DNA Methyltransferases

5. Structure and Function of DNA Methyltransferases

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3. A SAM analogue-utilizing ribozyme for site-specific RNA alkylation in living cells;Nature Chemistry;2023-09-04

4. DNA Labeling Using DNA Methyltransferases;Advances in Experimental Medicine and Biology;2022

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