Phosphorylation of covalent organic framework nanospheres for inhibition of amyloid-β peptide fibrillation-Reference-Cited by-同舟云学术

Phosphorylation of covalent organic framework nanospheres for inhibition of amyloid-β peptide fibrillation

Published:2022 Issue:20 Volume:13 Page:5902-5912
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Yao Linli¹,Zhou Zhe²,Wang Suxiao¹^ORCID,Zou Qichao¹,Wang Hang-Xing¹^ORCID,Ma Li-Xin³,Wang Shengfu¹^ORCID,Zhang Xiuhua¹^ORCID

Affiliation:

1. Collaborative Innovation Center for Advanced Organic Chemical Materials Co-constructed by the Province and Ministry, College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China

2. Department of Neurology, The First Hospital of Lanzhou University, Lanzhou, 730000, China

3. State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Science, Hubei University, Wuhan, 430062, China

Abstract

Nanoscale spherical COFs via phosphorylation functionalization were found to efficiently inhibit fibrillation of the Alzheimer's disease-associated Aβ peptide.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC00253A

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