Benzothiazole derivatives augment glucose uptake in skeletal muscle cells and stimulate insulin secretion from pancreatic β-cells via AMPK activation-Reference-Cited by-同舟云学术

Benzothiazole derivatives augment glucose uptake in skeletal muscle cells and stimulate insulin secretion from pancreatic β-cells via AMPK activation

Published:2014 Issue:76 Volume:50 Page:11222-11225
ISSN:1359-7345
Container-title:Chem. Commun.
language:en
Short-container-title:Chem. Commun.

Author:

Pasternak L.¹²³⁴⁵,Meltzer-Mats E.⁶⁷⁸⁹,Babai-Shani G.¹²³⁴⁵,Cohen G.¹²³⁴⁵,Viskind O.⁶⁷⁸⁹,Eckel J.¹⁰¹¹¹²¹³,Cerasi E.¹⁴¹⁵¹⁶¹⁷,Sasson S.¹²³⁴⁵,Gruzman A.⁶⁷⁸⁹

Affiliation:

1. Department of Pharmacology

2. Institute for Drug Research

3. School of Pharmacy

4. Faculty of Medicine

5. The Hebrew University of Jerusalem

6. Department of Chemistry

7. Faculty of Exact Sciences

8. Bar-Ilan University

9. Ramat-Gan, Israel

10. German Diabetes Center

11. Integrative Physiology

12. Paul-Langerhans-Group

13. Düsseldorf, Germany

14. The Endocrinology and Metabolism Service

15. Department of Medicine

16. Hadassah-Hebrew University Medical Center

17. Jerusalem, Israel

Abstract

Development of the unique bi-functional AMPK activators (glucose uptake and insulin secretion enhancers) for potential antidiabetic treatment.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2014/CC/C4CC03310H

Reference27 articles.

1. Glycaemic control in type 2 diabetes: Targets and new therapies

2. Contributions of β-Cell Dysfunction and Insulin Resistance to the Pathogenesis of Impaired Glucose Tolerance and Impaired Fasting Glucose

3. Advances in Pharmacologic Therapies for Type 2 Diabetes

4. Adenosine Monophosphate-Activated Protein Kinase (AMPK) as a New Target for Antidiabetic Drugs: A Review on Metabolic, Pharmacological and Chemical Considerations

5. Role of AMPK in pancreatic beta cell function

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