Polarization of macrophages to an anti-cancer phenotype through <i>in situ</i> uncaging of a TLR 7/8 agonist using bioorthogonal nanozymes-Reference-Cited by-同舟云学术

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Polarization of macrophages to an anti-cancer phenotype through in situ uncaging of a TLR 7/8 agonist using bioorthogonal nanozymes

Published:2024 Issue:7 Volume:15 Page:2486-2494
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Zhang Xianzhi¹^ORCID,Liu Yuanchang¹,Jiang Mingdi¹^ORCID,Mas-Rosario Javier A.¹²,Fedeli Stefano¹,Cao-Milan Roberto¹,Liu Liang¹,Winters Kyle J.¹,Hirschbiegel Cristina-Maria¹^ORCID,Nabawy Ahmed¹^ORCID,Huang Rui¹,Farkas Michelle E.¹²^ORCID,Rotello Vincent M.¹²^ORCID

Affiliation:

1. Department of Chemistry, University of Massachusetts Amherst, 710 N. Pleasant St., Amherst, MA 01003, USA

2. Molecular and Cellular Biology Graduate Program, University of Massachusetts Amherst, 230 Stockbridge Road, Amherst, Massachusetts, 01003, USA

Abstract

Polarization of macrophage to M1 phenotype by in situ activation of imiquimod using bioorthogonal nanozymes for anticancer therapy.

Funder

University of Massachusetts Amherst

National Institutes of Health

University of Massachusetts

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D3SC06431J

Reference86 articles.

1. Effects of engineered nanoparticles on the innate immune system

2. Delivery of drugs, proteins, and nucleic acids using inorganic nanoparticles

3. Protective and pathogenic functions of macrophage subsets

4. Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

5. Exploring the full spectrum of macrophage activation

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1. Sarcoidosis and Cancer: The Role of the Granulomatous Reaction as a Double-Edged Sword;Journal of Clinical Medicine;2024-09-04

2. Nanosensor-Enabled Detection and Identification of Intracellular Bacterial Infections in Macrophages;Biosensors;2024-07-25

3. Nanozymes in cancer immunotherapy: metabolic disruption and therapeutic synergy;Journal of Materials Chemistry B;2024

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