De Novo Synthesis of Inherently Chiral Heteracalix[4]aromatics from Enantioselective Macrocyclization Enabled by Chiral Phosphoric Acid-Catalyzed Intramolecular SNAr Reaction
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Published:2024
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ISSN:2041-6520
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Container-title:Chemical Science
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language:en
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Short-container-title:Chem. Sci.
Author:
Li Xingchi,Cheng Ying,Wang Xu-Dong,Tong Shuo,Wang Mei-Xiang
Abstract
We report herein the synthesis of highly enantiopure inherently chiral N3,O-calix[2]arene[2]triazines from enantioselective macrocyclization enabled by chiral phosphoric acid-catalyzed intramolecular nucleophilic aromatic substitution reaction. In contrast to documented examples, inherent...
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry