Deciphering potential vascularization factors of on-chip co-cultured hiPSC-derived cerebral organoids-Reference-Cited by-全球学者库

Deciphering potential vascularization factors of on-chip co-cultured hiPSC-derived cerebral organoids

Published:2024 Issue: Volume: Page:
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Shaji Maneesha¹^ORCID,Tamada Atsushi²^ORCID,Fujimoto Kazuya¹^ORCID,Muguruma Keiko²^ORCID,Karsten Stanislav L.¹,Yokokawa Ryuji¹^ORCID

Affiliation:

1. Department of Micro Engineering, Graduate School of Engineering, Kyoto University, Kyoto daigaku-Katsura, Nishikyo-ku, Kyoto – 615-8540, Japan

2. Department of iPS Cell Applied Medicine, Kansai Medical University, 2-5-1 Shin-machi, Hirakata City, Osaka – 573-1010, Japan

Abstract

The first global analysis of the cerebral organoid (CO) response to 3D microvasculature indicates elaborate crosstalk between COs and ECs and points out potential vascularization factors for brain organoid vascularization on a chip.

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

NOVARTIS Foundation (Japan) for the Promotion of Science

Japan International Cooperation Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2024/LC/D3LC00930K

Reference86 articles.

1. Modeling Developmental Brain Diseases Using Human Pluripotent Stem Cells-Derived Brain Organoids – Progress and Perspective

2. Engineering organoids

3. Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex

4. Cell stress in cortical organoids impairs molecular subtype specification

5. An in vivo model of functional and vascularized human brain organoids