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A microfluidic platform for quantitative measurements of effective protein charges and single ion binding in solution

  • Published:2015 Issue:18 Volume:17 Page:12161-12167
  • ISSN:1463-9076
  • Container-title:Physical Chemistry Chemical Physics
  • language:en
  • Short-container-title:Phys. Chem. Chem. Phys.

Author:

Herling Therese W.1234,Arosio Paolo1234,Müller Thomas1234,Linse Sara5678,Knowles Tuomas P. J.1234

Affiliation:

1. Department of Chemistry

2. University of Cambridge

3. Cambridge

4. UK

5. Department of Biochemistry and Structural Biology

6. Lund University

7. Lund

8. Sweden

Abstract

Microfluidic electrophoresis enables the comparison of dry sequence and solvated protein charges, and the detection of protein–ion binding.

Funder

European Research Council

Biotechnology and Biological Sciences Research Council

Swedish Research Council Formas

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Cited by 18 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Nonspecificity fingerprints for clinical-stage antibodies in solution;Proceedings of the National Academy of Sciences;2023-12-18

2. Non-specificity fingerprints for clinical stage antibodies in solution;2023-02-14

3. Microscale Diffusiophoresis of Proteins;The Journal of Physical Chemistry B;2022-10-28

4. Pharmaceutical Industry;Industry 4.0 Vision for Energy and Materials;2022-05-13

5. Diffusional microfluidics for protein analysis;TrAC Trends in Analytical Chemistry;2022-01
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