Leak-free million-fold DNA amplification with locked nucleic acid and targeted hybridization in one pot

Author:

Komiya K.1234ORCID,Komori M.56784,Noda C.1234,Kobayashi S.910114,Yoshimura T.56784,Yamamura M.1234

Affiliation:

1. School of Computing

2. Tokyo Institute of Technology

3. Yokohama

4. Japan

5. Research and Development

6. Abbott Japan Co.

7. Ltd

8. Chiba 270-2214

9. Department of Communication Engineering and Informatics

10. the University of Electro-Communications

11. Tokyo 182-8585

Abstract

The leak-free DNA amplification reaction supplies a large quantity of single-stranded DNA for directing molecular nanodevices in response to nucleic acid stimuli.

Funder

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology

Japan Science and Technology Agency

Cabinet Office, Government of Japan

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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