Recognition of shorter and longer trimethyllysine analogues by epigenetic reader proteins-Reference-Cited by-同舟云学术

Recognition of shorter and longer trimethyllysine analogues by epigenetic reader proteins

Published:2018 Issue:19 Volume:54 Page:2409-2412
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Al Temimi Abbas H. K.¹²³⁴^ORCID,Belle Roman¹²³⁴,Kumar Kiran⁵⁶⁷⁸^ORCID,Poater Jordi⁹¹⁰¹¹¹²¹³^ORCID,Betlem Peter¹²³⁴,Pieters Bas J. G. E.¹²³⁴,Paton Robert S.⁵⁶⁷⁸^ORCID,Bickelhaupt F. Matthias¹²³⁴¹⁴^ORCID,Mecinović Jasmin¹²³⁴^ORCID

Affiliation:

1. Institute for Molecules and Materials

2. Radboud University

3. Nijmegen 6525 AJ

4. The Netherlands

5. Chemistry Research Laboratory

6. University of Oxford

7. Oxford OX1 3TA

8. UK

9. ICREA

10. Barcelona 08010

11. Spain

12. Departament de Química Inorgànica i Orgànica & IQTCUB

13. Universitat de Barcelona

14. Department of Theoretical Chemistry and Amsterdam Center for Multiscale Modeling (ACMM)

Abstract

Combined thermodynamic data, molecular dynamics simulations, and quantum chemical studies reveal that epigenetic reader proteins efficiently bind trimethylornithine and trimethylhomolysine.

Funder

H2020 European Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Ministerio de Economía y Competitividad

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CC/C8CC01009A

Reference23 articles.

1. Regulation of chromatin by histone modifications

2. Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact

3. SET domain protein lysine methyltransferases: Structure, specificity and catalysis

4. Molecular mechanisms and potential functions of histone demethylases

5. How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers

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