Copper-catalyzed direct C–H phosphorylation of N-imino isoquinolinium ylides with H-phosphonates

Author:

Zhan Xin-Chen1234,Hei Yu-Yuan1234,Song Jian-Lan1234,Qian Peng-Cheng1234,Zhang Xing-Guo1234ORCID,Deng Chen-Liang1234ORCID

Affiliation:

1. College of Chemistry and Materials Engineering

2. Wenzhou University

3. Wenzhou 325035

4. China

Abstract

A new and efficient method for the synthesis of phosphorus-containing isoquinoline skeletons via copper-catalyzed direct C–H phosphorylation of isoquinoline N-amides with H-phosphonates has been described.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference46 articles.

1. A Guide to Organophosphorus Chemistry , ed. L.-D. Quin , John Wiley & Sons , Toronto , 2000

2. The Chemistry of Organophosphorus Compounds , ed. F. H. Hartley , Wiley , New York , 1996

3. Review on Modern Advances of Chemical Methods for the Introduction of a Phosphonic Acid Group

4. Synthetic Methods for Azaheterocyclic Phosphonates and Their Biological Activity

5. P-Chiral Oligonucleotides in Biological Recognition Processes

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