Understanding the molecular mechanism of the stereoselective conversion of N-trialkylsilyloxy nitronates into bicyclic isoxazoline derivatives-Reference-Cited by-同舟云学术

Understanding the molecular mechanism of the stereoselective conversion of N-trialkylsilyloxy nitronates into bicyclic isoxazoline derivatives

Published:2021 Issue:21 Volume:45 Page:9491-9500
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Kącka-Zych Agnieszka¹²³⁴⁵^ORCID,Jasiński Radomir¹²³⁴⁵

Affiliation:

1. Cracow University of Technology

2. Institute of Organic Chemistry and Technology

3. Warszawska 24

4. 31-155 Cracow

5. Poland

Abstract

The conversion of N-trialkylsilyloxy nitronates into bicyclic isoxazoline derivatives has been explored using the density functional theory method within the context of molecular electron density theory at the ωB97XD(PCM)/6-311G(d,p) level.

Funder

Infrastruktura PL-Grid

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D1NJ01198G

Reference52 articles.

1. In vivo and in vitro ADMET profiling and in vivo pharmacodynamic investigations of a selective α7 nicotinic acetylcholine receptor agonist with a spirocyclic Δ 2 -isoxazoline molecular skeleton

2. Synthesis, Antimicrobial and Antioxidant Activities of 2-Isoxazoline Derivatives

3. Synthesis of functionalized 2-isoxazolines as three-dimensional fragments for fragment-based drug discovery

4. Synthesis and antiphytoviral activity of α-aminophosphonates containing 3, 5-diphenyl-2-isoxazoline as potential papaya ringspot virus inhibitors

5. Antitubercular nitrofuran isoxazolines with improved pharmacokinetic properties

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Dual docking of some synthesized isoxazolidine derivatives against Cathepsin L and main protease as a novel treatment strategy for COVID-19;Journal of Molecular Structure;2024-03

2. Understanding the Molecular Mechanism of Thermal and LA-Catalysed Diels–Alder Reactions between Cyclopentadiene and Isopropyl 3-Nitroprop-2-Enate;Molecules;2023-07-08

3. Fully Selective Synthesis of Spirocyclic-1,2-oxazine N-Oxides via Non-Catalysed Hetero Diels-Alder Reactions with the Participation of Cyanofunctionalysed Conjugated Nitroalkenes;Molecules;2023-06-06

4. Nitrile Oxide, Alkenes, Dipolar Cycloaddition, Isomerization and Metathesis Involved in the Syntheses of 2-Isoxazolines;Molecules;2023-03-10

5. On the question of selective protocol for the preparation of juglone via (4+2) cycloaddition involving 3-hydroxypyridazine: DFT mechanistic study;Chemistry of Heterocyclic Compounds;2023-03