A gold-catalyzed facile intramolecular rearrangement and cyclization sequence for synthesis of 2,5-dihydrofurans

Author:

Sunil Komalla1234,Thummala Yadagiri12345,Dalovai Purnachandar12345,Balasubramanian Sridhar6234,Karunakar Galla V.12345ORCID

Affiliation:

1. Department of Fluoro and Agrochemicals

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad

4. India

5. Academy of Scientific and Innovative Research

6. Center for X-ray Crystallography

Abstract

An efficient gold-catalyzed intramolecular rearrangement and cyclization protocol was developed for synthesis of 2,5-dihydrofuran derivatives via formation of a new C–C and C–O bond with a quaternary centre.

Funder

Department of Science and Technology, Ministry of Science and Technology

Council of Scientific and Industrial Research, India

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference70 articles.

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2. X. L. Hou , Z.Yang and H. N. C.Wong , in Progress in Heterocyclic Chemistry , ed. G. W. Gribble and T. L. Gilchrist , Pergamon , Oxford , 2003 , vol. 15 , p. 167

3. A. Boto and L.Alvarez , in Heterocycles in Natural Product Synthesis , ed. K. C. Majumdar and S. K. Chattopadhyay , Wiley- VCH , Weinheim , 2011

4. D. C. Ayres and J. D.Loike , Chemistry and pharmacology of natural products. Lignans: chemical, biological and clinical properties , Cambridge University Press , Cambridge , 1990

5. Handbook of Marine Natural Products , ed. E. Fattorusso , W. H. Gerwick and O. Taglialatela-Scafati , Springer , Dordrecht , 2012

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